Crohn’s Disease is an irritable bowel disease with an unknown cause. Yet, the primary culprit is inflammation in the gastrointestinal (GI) tract. This can be anywhere from your esophagus, stomach, small intestine, and the large intestine (colon).
However, the most commonly affected regions are the ileum, which is the very last part of the small intestine, and the first portion of the colon.
The standard theory about Crohn’s Disease is that it involves genetic irregularities in the programming for the immune system. These irregularities can be triggered by environmental factors.
However, recent research on the human microbiome has discovered that a dysbiosis of bacteria in the gut has a major role to play in the disease.